StATS: Interesting quote: It seems to me reasonable... (March 10, 2005) Category: Quotations

It seems to me reasonable to look for evidence of benefit or harm in certain biologically plausible subgroups, even though the statistical basis for this evidence is not compelling. It is ludicrous and economically mad that we have to treat 1000 patients to benefit six because our trial methodology cannot cope. An intelligent review of subgroups would allow this ratio to be much more reasonable. Desmond G Julian, Debate: A subversive view of subsets - a dissident clinician's opinion. Curr Control Trials Cardiovasc Med 2000: 1(1); 28-30. [Medline] [Abstract] [Full text] [PDF]

Creative Commons License This work is licensed under a Creative Commons Attribution 3.0 United States License. It was written by Steve Simon.~~~

This page was written by Steve Simon while working at Children's Mercy Hospital. Although I do not hold the copyright for this material, I am reproducing it here as a service, as it is no longer available on the Children's Mercy Hospital website. Need more information? I have a page with general help resources. You can also browse for pages similar to this one at