Interesting quote: In the end... (March 10, 2005)

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In the end there is no escape from a return to "the expert," who tells us which trial to believe, not only on the basis of methodology but also on the basis of insights in pathophysiology, pharmacology, and perhaps type of publication (supplements, special interest or "throw away" journals, etc). All that we can ask from the expert is a careful explanation of what arguments he or she used in accepting or dismissing the evidence from certain trials. Jan P Vandenbroucke, Experts’ views are still needed, BMJ 1998;316:469 (7 February) [Full text]